General description

Native β₂-microglobulin from human urine. A useful marker for the determination of AIDS progression in HIV-infected subjects. Increased levels may also indicate increased proliferation of tumor masses.

Native β₂-microglobulin from human urine. Single chain polypeptide that is the constant component of Class I MHC, which is located on most nucleated cells. It is also a normal constituent of serum and urine. Increased levels of this protein in the serum are used as a marker for impairments of renal function and a variety of lymphoproliferative diseases.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Zabay, J.M., et al. 1995. J. Acquired Immune Defic. Syndr. Hum. Retrovirol. 8, 266.Mady, B.J., et al. 1991. J. Immunol.147, 3139.Lampson, L.A. 1990. J. Immunol. 144, 512.Calzia, R., et al. 1989. Adv. Exp. Med. Biol.257, 225.Ninomiya, Y., and Arakawa, M. 1989. Diabetes Res.10, 129.

Packaging

100, 250 µg in Plastic ampoule

Physical form

In PBS, 150 mM NaCl, 20 mM phosphate buffer, pH 7.3.

Preparation Note

Prepared from urine that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, product can be stored at 4°C for up to 6 months.

Warning

Toxicity: Standard Handling (A)